Routes and types of microbial infection in the pathology of pancreatic adenocarcinoma

Introduction/Objective. Pancreatic cancer may be accompanied by infections caused various microorganisms. It is uncertain wheatear pancreatic infection precedes the development of or vice versa. The aim this study to analyze routes from duodenum through duct determine what types microorganisms can get into pancreas and nearby tissue. Methods. In patients subjected cephalic duodenopancreatectomy (Whipple procedure) due adenocarcinoma ampulla Vater, head pancreas, swabs duodenal mucosa, duct, tissue at line resection were taken. Microscopic slides prepared directly patients? specimens as well colonies on culture plates, both Gram stained. Results. Candida was present in all three (duodenum, tissue), while bacteria, depending species (Pseudomonas aeruginosa, ?-hemolytic Streptococcus, coagulasenegative Staphylococcus, Enterococcus spp., Serratia spp.), tissue, but not duodenum. Conclusion. There a connection between presence pathology adenocarcinoma. Results show that originates duodenum, bacterial originate blood injuries.